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Combo-pilling is the newest fad or in addition to this the newest to come under scrutiny and so it is just more publicly known although in the past, comb-pilling for weight loss has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular is the fact that as of right now there aren't any long term prescription weight loss supplements that have been approved by the FDA other than orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications however some of the combinations happen to be rejected or have yet to be licensed by the FDA. Seizures can be a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug also can raise hypertension and heart rate, and shouldn't be used in individuals with a history of heart attack or stroke in the previous six months. 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