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Using two separate drugs to lose weight naturally can be very effective you will find combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the individuals who go through it you ought to err on the side of caution and permit the FDA do its job and demand some investigation be done in order that the public knows the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies have been in business to earn money and that they would say almost anything to keep people on the medications. Researchers found that participants taking this drug for any year, lost weight within four weeks and have kept the load off during the entire 56 weeks of the study. Contrave can be a combination of the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs that are made up of multiple active ingredient, which may make them more potent and safer. Combo-pilling may be the newest fad or in addition to this the newest to come under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular will be the fact that as of right now there aren't long term prescription diet pills that have been approved by the FDA besides orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be licensed by the FDA. Seizures are a side effect with Contrave and must not be taken in those with seizure disorders. The drug can also raise blood pressure and pulse rate, and shouldn't be used in people who have a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure levels and pulse rate and must not used in patients with uncontrolled high blood pressure levels, and also by you are not heart-related and cerebrovascular (blood vessel dysfunction impacting the brain) disease. Patients having a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert medical researchers and patients on the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stopping smoking. The most common unwanted effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.